Our Benfica vs Bayer Leverkusen Prediction: 2-2
Benfica vs Bayer Leverkusen in the UEFA Champions League is scheduled for an 20:00 GMT kick-off on Wednesday November 5, 2025. We expect a 2-2 result in a tightly contested match, with BTTS looking like a reliable bet given both teams’ recent scoring form.
This Benfica vs Bayer Leverkusen prediction is backed by a deep dive into both teams' recent performances, key stats and head-to-head history — all of which you'll find detailed below to help you make an informed betting decision.
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Recent Form Insights
Benfica's Last Match – Guimaraes vs Benfica
Determined to maintain their recent success, Benfica must win following their 3-0 Portugal Primeira Liga victory against Guimaraes on November 1. In that match, Benfica had 66% possession and 14 attempts at goal, with 10 on target.
| Team | Possession | Shots (on target) | xG | Dangerous Attacks |
|---|---|---|---|---|
 Guimaraes | 34% | 7 (4) | 0.41 | 21 |
 Benfica | 66% | 14 (10) | 1.93 | 60 |
Bayer Leverkusen's Last Match – Bayern Munich vs Bayer Leverkusen
Bayer Leverkusen must win as they aim to bounce back from a disappointing 0-3 Germany Bundesliga I defeat against Bayern Munich on November 1. In that match, Bayer Leverkusen recorded 41% possession, attempting 3 shots on goal, with 1 hitting the target.
| Team | Possession | Shots (on target) | xG | Dangerous Attacks |
|---|---|---|---|---|
 Bayern Munich | 59% | 11 (4) | 1.71 | 82 |
 Bayer Leverkusen | 41% | 3 (1) | 0.11 | 30 |
Benfica vs Bayer Leverkusen Stats
Key Stats
| Benfica | Bayer Leverkusen | |
|---|---|---|
| 0.9 | Attacking Strength | 0.84 |
| 1.48 | Defence Strength | 0.9 |
| 2 | Points Per Game | 1.8 |
| 6/10 | WIN | 5/10 |
| 2/10 | DRAW | 3/10 |
| 6/10 | Clean Sheets | 2/10 |
| 2/10 | BTTS | 7/10 |
| 6/10 | Over 2.5 Goals | 6/10 |
| 1.9 | Average Scored | 2 |
Goals Scored vs Goals Conceded
Benfica are averaging 1.9 goals scored and 0.6 conceded per match, while Bayer Leverkusen average 2.0 scored and 2.0 conceded per game.
Benfica 19-6
Bayer Leverkusen 20-20
What are the odds for this match?
Benfica to win: @2
Draw: @3.5
Bayer Leverkusen to win: @3.6
Lineups
Benfica (4-2-3-1) : Anatoliy Trubin, Fredrik Aursnes, Tomas Araujo, Nicolas Otamendi, Samuel Dahl, Richard Rios, Enzo Barrenechea, Dodi Lukebakio, Leandro Barreiro, Georgiy Sudakov, Vangelis Pavlidis
Bayer Leverkusen (3-4-2-1) : Mark Flekken, Jarell Quansah, Loic Bade, Edmond Tapsoba, Arthur, Aleix Garcia, Ibrahim Maza, Alex Grimaldo, Claudio Echeverri, Ernest Poku, Christian Michel Kofane