Our CA Independiente vs San Lorenzo Prediction: 1-0
CA Independiente vs San Lorenzo in the Argentina Liga Profesional is scheduled for an 17:30 GMT kick-off on Sunday September 21, 2025. A hard-fought battle awaits, but CA Independiente is likely to edge past San Lorenzo with a narrow 1-0 scoreline.
Our prediction is supported by key performance data, betting odds and match insights — everything you need is right below to make smarter bets.
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Recent Form Insights
CA Independiente's Last Match – CA Independiente vs Banfield
CA Independiente must win as they aim to bounce back from a disappointing 0-1 Argentina Liga Profesional defeat against Banfield on September 13. In that match, CA Independiente saw 68% of the ball and created 9 goal attempts, with 3 on target.
| Team | Possession | Shots (on target) | xG | Dangerous Attacks |
|---|---|---|---|---|
 CA Independiente | 68% | 9 (3) | 0.48 | 70 |
 Banfield | 32% | 7 (4) | 0.39 | 27 |
San Lorenzo's Last Match – Racing Club vs San Lorenzo
San Lorenzo will look to get back on track following a 0-2 Argentina Liga Profesional loss against Racing Club on September 12. In that match, San Lorenzo controlled 48% of possession and managed 3 shots on goal, with 1 hitting the target.
| Team | Possession | Shots (on target) | xG | Dangerous Attacks |
|---|---|---|---|---|
 Racing Club | 52% | 4 (4) | 1.36 | 28 |
 San Lorenzo | 48% | 3 (1) | 0.27 | 28 |
CA Independiente vs San Lorenzo Stats
Key Stats
| CA Independiente | San Lorenzo | |
|---|---|---|
| 1 | Attacking Strength | 0.7 |
| 0.47 | Defence Strength | 0.82 |
| 0.4 | Points Per Game | 1.3 |
| 0/10 | WIN | 3/10 |
| 4/10 | DRAW | 4/10 |
| 3/10 | Clean Sheets | 6/10 |
| 3/10 | BTTS | 2/10 |
| 3/10 | Over 2.5 Goals | 2/10 |
| 0.4 | Average Scored | 0.5 |
Goals Scored vs Goals Conceded
CA Independiente are averaging 0.4 goals scored and 1.1 conceded per match, while San Lorenzo average 0.5 scored and 0.6 conceded per game.
CA Independiente 4-11
San Lorenzo 5-6
What are the odds for this match?
CA Independiente to win: @2.1
Draw: @2.9
San Lorenzo to win: @4.2
Lineups
CA Independiente (4-2-3-1) : Rodrigo Rey, Federico Vera, Facundo Zabala, Ivan Marcone, Kevin Lomonaco, Sebastian Valdez, Santiago Montiel, Pablo Galdames, Gabriel Avalos, Matias Abaldo, Diego Tarzia
San Lorenzo (4-1-4-1) : Orlando Gill, Fabricio Gabriel Lopez, Baez, Ignacio Peruzzi, Jhohan Romana, Gaston Hernandez, Ezequiel Cerutti, Nicolas Tripichio, Alexis Cuello, Facundo Gulli, Matias Reali
Rosario Central 
Lanus 
Deportivo Riestra 
Velez Sarsfield 
San Lorenzo 
River Plate 
Gimnasia LP 
CA Talleres de Córdoba 
Sarmiento 
San Martin SJ 
CA Independiente 
Atlético Tucumán 
Instituto AC Cordoba 
Godoy Cruz 
Platense