Our Independiente Medellin vs Independiente Santa Fe Prediction: 2-2
Independiente Medellin vs Independiente Santa Fe in the Colombia Primera A is scheduled for an 01:10 GMT kick-off on Tuesday October 21, 2025. A 2-2 draw is our predicted outcome, with both teams expected to score, making BTTS a solid betting option.
Our prediction is supported by key Independiente Medellin vs Independiente Santa Fe stats, including attacking and defensive strength, recent form and historical results — all detailed below.
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Recent Form Insights
Independiente Medellin's Last Match – Independiente Medellin vs Fortaleza CEIF
Determined to maintain their recent success, Independiente Medellin must win following their 3-1 Colombia Primera A victory against Fortaleza CEIF on October 17. In that match, Independiente Medellin recorded 56% possession, attempting 10 shots on goal, with 9 hitting the target.
| Team | Possession | Shots (on target) | xG | Dangerous Attacks |
|---|---|---|---|---|
 Independiente Medellin | 56% | 10 (9) | 1.54 | 41 |
 Fortaleza CEIF | 44% | 9 (5) | 0.54 | 27 |
Independiente Santa Fe's Last Match – Boyaca Chico vs Independiente Santa Fe
Independiente Santa Fe will be determined to find a winning touch after a 0-0 Colombia Primera A draw against Boyaca Chico on October 18. In that match, Independiente Santa Fe recorded 52% possession, firing 13 shots at goal, with 4 on target.
| Team | Possession | Shots (on target) | xG | Dangerous Attacks |
|---|---|---|---|---|
 Boyaca Chico | 48% | 7 (2) | - | 26 |
 Independiente Santa Fe | 52% | 13 (4) | - | 54 |
Independiente Medellin vs Independiente Santa Fe Stats
Key Stats
| Independiente Medellin | Independiente Santa Fe | |
|---|---|---|
| 1.37 | Attacking Strength | 1.29 |
| 1.61 | Defence Strength | 0.84 |
| 1.8 | Points Per Game | 1.5 |
| 5/10 | WIN | 4/10 |
| 3/10 | DRAW | 3/10 |
| 2/10 | Clean Sheets | 3/10 |
| 8/10 | BTTS | 5/10 |
| 9/10 | Over 2.5 Goals | 5/10 |
| 2.1 | Average Scored | 1.4 |
Goals Scored vs Goals Conceded
Independiente Medellin are averaging 2.6 goals scored and 1.5 conceded per match, while Independiente Santa Fe average 1.4 scored and 1.1 conceded per game.
Atletico Nacional Medellin 
Deportivo Pasto 
America de Cali 
Once Caldas 
Deportes Tolima 
Junior 
Atletico Bucaramanga 
Deportivo Cali 
Aguilas Doradas 
Llaneros 
Independiente Santa Fe 
Fortaleza CEIF 
Jaguares de Cordoba 
Millonarios 
Independiente Medellin 
Cucuta Deportivo 
Deportivo Pereira 
Boyaca Chico