Our La Serena vs Universidad de Chile Prediction: 1-2
La Serena vs Universidad de Chile in the Chile Liga de Primera is scheduled for an 18:00 GMT kick-off on Sunday September 28, 2025. We anticipate a 1-2 away victory, but given both teams’ ability to score, BTTS seems like a valuable betting option.
This La Serena vs Universidad de Chile prediction is backed by a deep dive into both teams' recent performances, key stats and head-to-head history — all of which you'll find detailed below to help you make an informed betting decision.
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Recent Form Insights
La Serena's Last Match – Deportes Limache vs La Serena
After suffering a 0-2 Chile Cup loss to Deportes Limache, La Serena must win to get back on track. In that match, La Serena controlled 40% of possession and managed 11 shots on goal, with 2 hitting the target.
| Team | Possession | Shots (on target) | xG | Dangerous Attacks |
|---|---|---|---|---|
Deportes Limache | 60% | 11 (3) | 0.72 | 40 |
 La Serena | 40% | 11 (2) | 1.26 | 47 |
Universidad de Chile's Last Match – Universidad de Chile vs Alianza Lima
Universidad de Chile will seek to keep their streak alive after a 2-1 Copa Sudamericana victory over Alianza Lima on September 26. In that match, Universidad de Chile recorded 49% possession, firing 7 shots at goal, with 5 on target.
| Team | Possession | Shots (on target) | xG | Dangerous Attacks |
|---|---|---|---|---|
 Universidad de Chile | 49% | 7 (5) | 1.09 | 41 |
 Alianza Lima | 51% | 4 (2) | 0.56 | 42 |
La Serena vs Universidad de Chile Stats
Key Stats
| La Serena | Universidad de Chile | |
|---|---|---|
| 0.84 | Attacking Strength | 1.21 |
| 1.58 | Defence Strength | 0.84 |
| 0.8 | Points Per Game | 1.7 |
| 2/10 | WIN | 5/10 |
| 2/10 | DRAW | 2/10 |
| 0/10 | Clean Sheets | 5/10 |
| 6/10 | BTTS | 3/10 |
| 5/10 | Over 2.5 Goals | 5/10 |
| 1.5 | Average Scored | 1.5 |
Goals Scored vs Goals Conceded
La Serena are averaging 1.5 goals scored and 1.9 conceded per match, while Universidad de Chile average 1.5 scored and 0.7 conceded per game.
La Serena 15-19
Universidad de Chile 15-7
What are the odds for this match?
La Serena to win: @4.333
Draw: @4.2
Universidad de Chile to win: @1.65
Lineups
La Serena (4-5-1) : Eryin Sanhueza, Andres Zanini, Nicolas Ferreyra, Lucas Alarcon, Juan Fuentes, Matias Pinto, Fernando Dinamarca, Sebastian Diaz Aracena, Jeisson Vargas, Sebastian Gallegos, Esteban Moreira
Universidad de Chile (4-3-3) : Cristopher Toselli, Nicolas Ramirez, Ignacio Tapia, Nicolas Fernandez, David Retamal, Antonio Diaz, Felipe Salomoni, Sebastian Rodriguez, Maximiliano Guerrero, Leandro Fernandez, Rodrigo Contreras
Coquimbo Unido 
Universidad Catolica 
Universidad de Chile 
O'Higgins 
Audax Italiano 
Palestino 
Colo Colo 
Cobresal 
Huachipato 
Nublense 
Union La Calera 
La Serena 
Everton de Vina 
Union Espanola 
Deportes Iquique