Our Sassuolo vs Lazio Prediction: 1-2
Sassuolo vs Lazio in the Italy Serie A is scheduled for an 16:00 GMT kick-off on Sunday September 14, 2025. Our analysis suggests a 1-2 away win, but with both teams likely to get on the scoresheet, BTTS is also worth considering.
This Sassuolo vs Lazio prediction is backed by a deep dive into both teams' recent performances, key stats and head-to-head history — all of which you'll find detailed below to help you make an informed betting decision.
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Recent Form Insights
Sassuolo's Last Match – Cremonese vs Sassuolo
Sassuolo will look to get back on track following a 2-3 Italy Serie A loss against Cremonese on August 29. In that match, Sassuolo recorded 58% possession, attempting 8 shots on goal, with 6 hitting the target.
| Team | Possession | Shots (on target) | xG | Dangerous Attacks |
|---|---|---|---|---|
 Cremonese | 42% | 8 (6) | 3.45 | 39 |
 Sassuolo | 58% | 8 (6) | 1.33 | 31 |
Lazio's Last Match – Lazio vs Verona
Lazio will hope to extend their good run following a 4-0 Italy Serie A win against Verona on August 31. In that match, Lazio recorded 70% possession, firing 13 shots at goal, with 6 on target.
| Team | Possession | Shots (on target) | xG | Dangerous Attacks |
|---|---|---|---|---|
 Lazio | 70% | 13 (6) | 3.82 | 44 |
 Verona | 30% | 6 (4) | 0.7 | 30 |
Sassuolo vs Lazio Stats
Key Stats
| Sassuolo | Lazio | |
|---|---|---|
| 0.78 | Attacking Strength | 1.11 |
| 1.8 | Defence Strength | 0.86 |
| 1.2 | Points Per Game | 1.5 |
| 3/10 | WIN | 4/10 |
| 3/10 | DRAW | 3/10 |
| 4/10 | Clean Sheets | 4/10 |
| 3/10 | BTTS | 3/10 |
| 3/10 | Over 2.5 Goals | 3/10 |
| 1.3 | Average Scored | 1.3 |
Goals Scored vs Goals Conceded
Sassuolo are averaging 1.3 goals scored and 1.0 conceded per match, while Lazio average 1.3 scored and 0.9 conceded per game.
Sassuolo 13-10
Lazio 13-9
What are the odds for this match?
Sassuolo to win: @3.6
Draw: @3.6
Lazio to win: @2
Over 2.5 Goals: @1.925
Lineups
Sassuolo (4-3-3) : Arijanet Muric, Sebastian Walukiewicz, Jay Idzes, Tarik Muharemovic, Josh Doig, Ismael Kone, Nemanja Matic, Aster Vranckx, Domenico Berardi, Andrea Pinamonti, Armand Lauriente
Lazio (4-3-3) : Ivan Provedel, Adam Marusic, Mario Gila, Alessio Romagnoli, Nuno Tavares, Matteo Guendouzi, Nicolo Rovella, Fisayo Dele-Bashiru, Matteo Cancellieri, Taty Castellanos, Mattia Zaccagni