Our Once Caldas vs Atletico Nacional Medellin Prediction: 1-2
Once Caldas vs Atletico Nacional Medellin in the Colombia Cup is scheduled for an 00:30 GMT kick-off on Friday October 10, 2025. A 1-2 result in favor of the away side is our top pick, yet with both teams creating chances, BTTS is a smart alternative bet.
Our prediction is supported by key Once Caldas vs Atletico Nacional Medellin stats, including attacking and defensive strength, recent form and historical results — all detailed below.
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Recent Form Insights
Once Caldas's Last Match – La Equidad vs Once Caldas
Determined to maintain their recent success, Once Caldas must win following their 1-0 Colombia Primera A victory against La Equidad on October 7. In that match, Once Caldas had 45% possession and 5 attempts at goal, with 2 on target.
| Team | Possession | Shots (on target) | xG | Dangerous Attacks |
|---|---|---|---|---|
 La Equidad | 55% | 6 (4) | 1.04 | 44 |
 Once Caldas | 45% | 5 (2) | 1.16 | 19 |
Atletico Nacional Medellin's Last Match – Boyaca Chico vs Atletico Nacional Medellin
Atletico Nacional Medellin will aim to turn their fortunes around after a 1-1 Colombia Primera A draw with Boyaca Chico on October 6. In that match, Atletico Nacional Medellin controlled 52% of possession and managed 15 shots on goal, with 6 hitting the target.
| Team | Possession | Shots (on target) | xG | Dangerous Attacks |
|---|---|---|---|---|
 Boyaca Chico | 48% | 6 (2) | 0.38 | 18 |
 Atletico Nacional Medellin | 52% | 15 (6) | 1.82 | 43 |
Once Caldas vs Atletico Nacional Medellin Stats
Key Stats
| Once Caldas | Atletico Nacional Medellin | |
|---|---|---|
| 1.46 | Attacking Strength | 1.82 |
| 1.14 | Defence Strength | 0.63 |
| 2.2 | Points Per Game | 1.7 |
| 7/10 | WIN | 4/10 |
| 1/10 | DRAW | 5/10 |
| 6/10 | Clean Sheets | 3/10 |
| 3/10 | BTTS | 6/10 |
| 4/10 | Over 2.5 Goals | 4/10 |
| 1.7 | Average Scored | 1.7 |
Goals Scored vs Goals Conceded
Once Caldas are averaging 1.7 goals scored and 0.7 conceded per match, while Atletico Nacional Medellin average 1.7 scored and 1.0 conceded per game.
Once Caldas 17-7
Atletico Nacional Medellin 17-10
What are the odds for this match?
Once Caldas to win: @2.625
Draw: @3.1
Atletico Nacional Medellin to win: @2.75
Deportivo Pereira 
Fortaleza CEIF 
Bogota FC 
Leones 
La Equidad