Our Inter Milan vs Sassuolo Prediction: 4-1
Inter Milan vs Sassuolo in the Italy Serie A is scheduled for an 18:45 GMT kick-off on Sunday September 21, 2025. A 4-1 win for the home side is our main prediction, though over 2.5 goals looks like a valuable bet given both teams’ attacking tendencies.
Our prediction is supported by key Inter Milan vs Sassuolo stats, including attacking and defensive strength, recent form and historical results — all detailed below.
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Recent Form Insights
Inter Milan's Last Match – Ajax vs Inter Milan
Inter Milan will aim to maintain their momentum following a 2-0 UEFA Champions League triumph against Ajax on September 17. In that match, Inter Milan recorded 43% possession, firing 9 shots at goal, with 4 on target.
| Team | Possession | Shots (on target) | xG | Dangerous Attacks |
|---|---|---|---|---|
 Ajax | 57% | 6 (2) | 1.32 | 34 |
 Inter Milan | 43% | 9 (4) | 1.21 | 34 |
Sassuolo's Last Match – Sassuolo vs Lazio
Determined to maintain their recent success, Sassuolo must win following their 1-0 Italy Serie A victory against Lazio on September 14. In that match, Sassuolo controlled 41% of possession and managed 4 shots on goal, with 3 hitting the target.
| Team | Possession | Shots (on target) | xG | Dangerous Attacks |
|---|---|---|---|---|
 Sassuolo | 41% | 4 (3) | 1.12 | 39 |
 Lazio | 59% | 8 (3) | 0.74 | 56 |
Inter Milan vs Sassuolo Stats
Key Stats
| Inter Milan | Sassuolo | |
|---|---|---|
| 1.55 | Attacking Strength | 0.78 |
| 0.86 | Defence Strength | 1.78 |
| 1.9 | Points Per Game | 1.4 |
| 6/10 | WIN | 4/10 |
| 1/10 | DRAW | 2/10 |
| 4/10 | Clean Sheets | 5/10 |
| 5/10 | BTTS | 2/10 |
| 6/10 | Over 2.5 Goals | 3/10 |
| 2.1 | Average Scored | 1.3 |
Goals Scored vs Goals Conceded
Inter Milan are averaging 2.1 goals scored and 1.2 conceded per match, while Sassuolo average 1.3 scored and 0.9 conceded per game.
Inter Milan 21-12
Sassuolo 13-9
What are the odds for this match?
Inter Milan to win: @1.27
Draw: @5.75
Sassuolo to win: @12
Lineups
Inter Milan (3-5-2) : Josep Martínez, Manuel Akanji, Francesco Acerbi, Carlos Augusto, Denzel Dumfries, Nicolo Barella, Hakan Calhanoglu, Petar Sucic, Federico Dimarco, Marcus Thuram, Francesco Pio Esposito
Sassuolo (4-3-3) : Arijanet Muric, Woyo Coulibaly, Jay Idzes, Tarik Muharemovic, Josh Doig, Ismael Kone, Nemanja Matic, Aster Vranckx, Domenico Berardi, Andrea Pinamonti, Armand Lauriente
Napoli 
Inter Milan 
AC Milan 
Roma 
Bologna 
Juventus 
Como 
Lazio 
Udinese 
Cremonese 
Atalanta 
Sassuolo 
Torino 
Cagliari 
Lecce 
Parma 
Pisa 
Genoa 
Verona 
Fiorentina