Our America de Cali vs Independiente Medellin Prediction: 1-2
America de Cali vs Independiente Medellin in the Colombia Primera A is scheduled for an 00:30 GMT kick-off on Friday November 28, 2025. We anticipate a 1-2 away victory, but given both teams’ ability to score, BTTS seems like a valuable betting option.
Our prediction is supported by key America de Cali vs Independiente Medellin stats, including attacking and defensive strength, recent form and historical results — all detailed below.
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Recent Form Insights
America de Cali's Last Match – Atletico Nacional Medellin vs America de Cali
America de Cali will be looking to bounce back after a 0-1 Colombia Primera A defeat against Atletico Nacional Medellin on November 21. In that match, America de Cali recorded 43% possession, firing 4 shots at goal, with 0 on target.
| Team | Possession | Shots (on target) | xG | Dangerous Attacks |
|---|---|---|---|---|
 Atletico Nacional Medellin | 57% | 16 (1) | 1.14 | 0 |
 America de Cali | 43% | 4 (0) | 0.19 | 0 |
Independiente Medellin's Last Match – Junior vs Independiente Medellin
Independiente Medellin will be eager to respond after suffering a 0-1 Colombia Primera A defeat at the hands of Junior on November 20. In that match, Independiente Medellin had 58% possession and 13 attempts at goal, with 0 on target.
| Team | Possession | Shots (on target) | xG | Dangerous Attacks |
|---|---|---|---|---|
 Junior | 42% | 6 (1) | 0.89 | 0 |
 Independiente Medellin | 58% | 13 (0) | 1.08 | 0 |
America de Cali vs Independiente Medellin Stats
Key Stats
| America de Cali | Independiente Medellin | |
|---|---|---|
| 1.02 | Attacking Strength | 2.32 |
| 0.81 | Defence Strength | 1.02 |
| 1.6 | Points Per Game | 2 |
| 5/10 | WIN | 6/10 |
| 1/10 | DRAW | 2/10 |
| 3/10 | Clean Sheets | 3/10 |
| 4/10 | BTTS | 6/10 |
| 6/10 | Over 2.5 Goals | 6/10 |
| 1.5 | Average Scored | 2.3 |
Goals Scored vs Goals Conceded
America de Cali are averaging 1.5 goals scored and 1.4 conceded per match, while Independiente Medellin average 2.3 scored and 1.1 conceded per game.
Atletico Bucaramanga 
Deportes Tolima 
Independiente Santa Fe 
Fortaleza CEIF