Our Atletico Nacional Medellin vs Independiente Santa Fe Prediction: 2-2
Atletico Nacional Medellin vs Independiente Santa Fe in the Colombia Primera A is scheduled for an 02:30 GMT kick-off on Saturday July 26, 2025. We predict a tightly contested 2-2 draw, with both teams getting on the scoresheet, making BTTS a strong betting option.
Our prediction is supported by key Atletico Nacional Medellin vs Independiente Santa Fe stats, including attacking and defensive strength, recent form and historical results — all detailed below.
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Recent Form Insights
Atletico Nacional Medellin's Last Match – Deportivo Pereira vs Atletico Nacional Medellin
Atletico Nacional Medellin must win as they aim to bounce back from a disappointing 1-2 Colombia Primera A defeat against Deportivo Pereira on July 23. In that match, Atletico Nacional Medellin recorded 59% possession, attempting 6 shots on goal, with 3 hitting the target.
| Team | Possession | Shots (on target) | xG | Dangerous Attacks |
|---|---|---|---|---|
 Deportivo Pereira | 41% | 9 (7) | 1.2 | 37 |
 Atletico Nacional Medellin | 59% | 6 (3) | 0.8 | 24 |
Independiente Santa Fe's Last Match – Independiente Santa Fe vs Aguilas Doradas
Independiente Santa Fe will aim to turn their fortunes around after a 0-0 Colombia Primera A draw with Aguilas Doradas on July 23. In that match, Independiente Santa Fe recorded 56% possession, firing 10 shots at goal, with 6 on target.
| Team | Possession | Shots (on target) | xG | Dangerous Attacks |
|---|---|---|---|---|
 Independiente Santa Fe | 56% | 10 (6) | 0.63 | 42 |
 Aguilas Doradas | 44% | 6 (2) | 0.57 | 39 |
Atletico Nacional Medellin vs Independiente Santa Fe Stats
Key Stats
| Atletico Nacional Medellin | Independiente Santa Fe | |
|---|---|---|
| 1.38 | Attacking Strength | 1.56 |
| 1.34 | Defence Strength | 1.07 |
| 1.1 | Points Per Game | 1.9 |
| 3/10 | WIN | 6/10 |
| 2/10 | DRAW | 1/10 |
| 3/10 | Clean Sheets | 3/10 |
| 5/10 | BTTS | 6/10 |
| 5/10 | Over 2.5 Goals | 6/10 |
| 0.9 | Average Scored | 1.3 |
Goals Scored vs Goals Conceded
Atletico Nacional Medellin are averaging 1.2 goals scored and 1.0 conceded per match, while Independiente Santa Fe average 1.3 scored and 0.8 conceded per game.
Atletico Nacional Medellin 12-10
Independiente Santa Fe 13-8
Lineups
Atletico Nacional Medellin: David Ospina, Jorman Campuzano, Alfredo Morelos, Andres Sarmiento, William Tesillo, Joan Castro, Cesar Haydar, Marino Hinestroza, Juan Arias, Mateus Uribe, Edwin Cardona
Independiente Santa Fe: Omar Fernandez, Daniel Torres, Emanuel Olivera, Andres Mosquera Marmolejo, Jhojan Torres, Elvis Perlaza, Jhon Wenceslao Melendez Murillo, Christian Mafla, Ewil Hernando Murillo Renteria, Harold Mosquera, Victor Moreno
Atletico Bucaramanga 
Deportes Tolima 
Independiente Santa Fe 
Fortaleza CEIF