Our Millonarios vs Independiente Santa Fe Prediction: 2-2
Millonarios vs Independiente Santa Fe in the Colombia Primera A is scheduled for an 01:30 GMT kick-off on Sunday September 7, 2025. A 2-2 result is our main prediction, but with both teams likely to score, BTTS is another strong betting choice.
This Millonarios vs Independiente Santa Fe prediction is backed by a deep dive into both teams' recent performances, key stats and head-to-head history — all of which you'll find detailed below to help you make an informed betting decision.
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Recent Form Insights
Millonarios's Last Match – Envigado FC vs Millonarios
Millonarios will be looking to bounce back after a 0-1 Colombia Cup defeat against Envigado FC on September 3. In that match, Millonarios saw 61% of the ball and created 9 goal attempts, with 4 on target.
| Team | Possession | Shots (on target) | xG | Dangerous Attacks |
|---|---|---|---|---|
 Envigado FC | 39% | 6 (4) | - | 30 |
 Millonarios | 61% | 9 (4) | - | 84 |
Independiente Santa Fe's Last Match – Independiente Santa Fe vs Once Caldas
Independiente Santa Fe will be eager to respond after suffering a 1-2 Colombia Primera A defeat at the hands of Once Caldas on September 2.
Millonarios vs Independiente Santa Fe Stats
Key Stats
| Millonarios | Independiente Santa Fe | |
|---|---|---|
| 0.94 | Attacking Strength | 1.46 |
| 1.25 | Defence Strength | 1.34 |
| 0.8 | Points Per Game | 1.6 |
| 2/10 | WIN | 4/10 |
| 2/10 | DRAW | 4/10 |
| 1/10 | Clean Sheets | 5/10 |
| 6/10 | BTTS | 4/10 |
| 6/10 | Over 2.5 Goals | 3/10 |
| 1.2 | Average Scored | 1 |
Goals Scored vs Goals Conceded
Millonarios are averaging 1.4 goals scored and 1.5 conceded per match, while Independiente Santa Fe average 0.9 scored and 0.9 conceded per game.
Millonarios 14-15
Independiente Santa Fe 9-9
Lineups
Millonarios: Samuel Martin, Alex Castro, Jorge Leguin Cabezas Hurtado, Nicolas Arevalo, Santiago Giordana, Stiven Vega, Jorge Arias, Sergio Mosquera, Beckham David Castro Espinosa, Diego Novoa, Danovis Banguero
Independiente Santa Fe: Jhon Wenceslao Melendez Murillo, Ewil Hernando Murillo Renteria, Yilmar Velasquez, Hugo Rodallega, Daniel Torres, Emanuel Olivera, Andres Mosquera Marmolejo, Christian Mafla, Omar Fernandez, Harold Mosquera, Victor Moreno
Atletico Bucaramanga 
Deportes Tolima 
Fortaleza CEIF 
Independiente Santa Fe