Our Sao Paulo vs LDU Quito Prediction: 2-1
Sao Paulo vs LDU Quito in the Copa Libertadores is scheduled for an 22:00 GMT kick-off on Thursday September 25, 2025. A 2-1 victory for the hosts is our top prediction, yet given both teams’ attacking form, BTTS seems like a smart betting choice.
This Sao Paulo vs LDU Quito prediction is backed by a deep dive into both teams' recent performances, key stats and head-to-head history — all of which you'll find detailed below to help you make an informed betting decision.
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Recent Form Insights
Sao Paulo's Last Match – Santos vs Sao Paulo
Sao Paulo will be eager to respond after suffering a 0-1 Brazil Serie A defeat at the hands of Santos on September 21. In that match, Sao Paulo recorded 56% possession, firing 3 shots at goal, with 1 on target.
| Team | Possession | Shots (on target) | xG | Dangerous Attacks |
|---|---|---|---|---|
 Santos | 44% | 9 (4) | 1.67 | 41 |
 Sao Paulo | 56% | 3 (1) | 0.27 | 26 |
LDU Quito's Last Match – LDU Quito vs Universidad Catolica del Ecuador
LDU Quito will hope to recover from their recent 2-4 Ecuador LigaPro Serie A setback against Universidad Catolica del Ecuador on September 21. In that match, LDU Quito controlled 57% of possession and managed 9 shots on target.
| Team | Possession | Shots (on target) | xG | Dangerous Attacks |
|---|---|---|---|---|
 LDU Quito | 57% | 0 (9) | 1.18 | 49 |
 Universidad Catolica del Ecuador | 43% | 0 (7) | 0.99 | 25 |
Sao Paulo vs LDU Quito Stats
Key Stats
| Sao Paulo | LDU Quito | |
|---|---|---|
| 1.05 | Attacking Strength | 1.23 |
| 0.67 | Defence Strength | 1.12 |
| 1.2 | Points Per Game | 1.4 |
| 3/10 | WIN | 4/10 |
| 3/10 | DRAW | 2/10 |
| 4/10 | Clean Sheets | 3/10 |
| 2/10 | BTTS | 4/10 |
| 1/10 | Over 2.5 Goals | 2/10 |
| 0.8 | Average Scored | 1.1 |
Goals Scored vs Goals Conceded
Sao Paulo are averaging 0.8 goals scored and 0.8 conceded per match, while LDU Quito average 1.1 scored and 1.0 conceded per game.
Sao Paulo 8-8
LDU Quito 11-10
What are the odds for this match?
Sao Paulo to win: @1.38
Draw: @4.2
LDU Quito to win: @10
Lineups
Sao Paulo (3-4-1-2) : Rafael, Sabino, Robert Arboleda, Alan Franco, Emiliano Rigoni, Damian Bobadilla, Pablo Maia, Enzo Diaz, Rodriguinho, Luciano, Ferreira
LDU Quito (3-5-2) : Gonzalo Valle, Gian Franco Allala Menendez, Ricardo Ade, Leonel Quinonez, Jose Quintero, Gabriel Villamil, Carlos Gruezo, Fernando Cornejo, Bryan Ramirez, Lisandro Alzugaray, Jeison Medina
Velez Sarsfield 
Penarol 
Olimpia Asuncion