Our Santos vs Sao Paulo Prediction: 1-1
Santos vs Sao Paulo in the Brazil Serie A is scheduled for an 23:30 GMT kick-off on Sunday September 21, 2025. A 1-1 draw is our predicted outcome, with both teams expected to score, making BTTS a solid betting option.
This Santos vs Sao Paulo prediction is backed by a deep dive into both teams' recent performances, key stats and head-to-head history — all of which you'll find detailed below to help you make an informed betting decision.
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Recent Form Insights
Santos's Last Match – Atletico Mineiro vs Santos
Santos will be hoping to return to winning ways after a 1-1 Brazil Serie A draw with Atletico Mineiro on September 14. In that match, Santos recorded 47% possession, attempting 9 shots on goal, with 5 hitting the target.
| Team | Possession | Shots (on target) | xG | Dangerous Attacks |
|---|---|---|---|---|
Atletico Mineiro | 53% | 12 (5) | 1.19 | 58 |
Santos | 47% | 9 (5) | 1.27 | 27 |
Sao Paulo's Last Match – LDU Quito vs Sao Paulo
Sao Paulo will look to get back on track following a 0-2 Copa Libertadores loss against LDU Quito on September 18. In that match, Sao Paulo recorded 59% possession, firing 6 shots at goal, with 4 on target.
| Team | Possession | Shots (on target) | xG | Dangerous Attacks |
|---|---|---|---|---|
LDU Quito | 41% | 2 (5) | 0.68 | 24 |
Sao Paulo | 59% | 6 (4) | 0.69 | 38 |
Santos vs Sao Paulo Stats
Key Stats
| Santos | Sao Paulo | |
|---|---|---|
| 0.71 | Attacking Strength | 1.05 |
| 1.34 | Defence Strength | 1 |
| 1.2 | Points Per Game | 1.5 |
| 3/10 | WIN | 4/10 |
| 3/10 | DRAW | 3/10 |
| 2/10 | Clean Sheets | 4/10 |
| 5/10 | BTTS | 3/10 |
| 6/10 | Over 2.5 Goals | 2/10 |
| 1 | Average Scored | 1 |
Goals Scored vs Goals Conceded
Santos are averaging 1.0 goals scored and 1.8 conceded per match, while Sao Paulo average 1.0 scored and 0.8 conceded per game.
Santos 10-18
Sao Paulo 10-8
What are the odds for this match?
Santos to win: @2.25
Draw: @3.1
Sao Paulo to win: @3.5
Lineups
Santos (4-2-3-1) : Gabriel Brazao, Mayke, Adonis Frias, Luan Peres, Gonzalo Escobar, Joao Schmidt, Ze Rafael, Victor Hugo, Benjamin Rollheiser, Guilherme, Lautaro Diaz
Sao Paulo (3-4-1-2) : Young, Rafael Toloi, Luan Santos, Sabino, Mailton, Alisson, Felipe Negrucci, Wendell, Rodriguinho, Ferreira, Juan Dinenno



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Bragantino
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