Our Liverpool vs Atletico Madrid Prediction: 2-1
Liverpool vs Atletico Madrid in the UEFA Champions League is scheduled for an 19:00 GMT kick-off on Wednesday September 17, 2025. We expect a 2-1 home win, but with both teams proving their offensive capabilities, BTTS is a solid alternative bet.
This Liverpool vs Atletico Madrid prediction is backed by a deep dive into both teams' recent performances, key stats and head-to-head history — all of which you'll find detailed below to help you make an informed betting decision.
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Recent Form Insights
Liverpool's Last Match – Burnley vs Liverpool
Liverpool will seek to keep their streak alive after a 1-0 England Premier League victory over Burnley on September 14. In that match, Liverpool recorded 81% possession, attempting 13 shots on goal, with 4 hitting the target.
| Team | Possession | Shots (on target) | xG | Dangerous Attacks |
|---|---|---|---|---|
 Burnley | 19% | 2 (0) | 0.13 | 15 |
 Liverpool | 81% | 13 (4) | 2.47 | 106 |
Atletico Madrid's Last Match – Atletico Madrid vs Villarreal
Atletico Madrid will be eager to build on their previous performance after securing a 2-0 Spain La Liga victory over Villarreal on September 13. In that match, Atletico Madrid controlled 61% of possession and managed 6 shots on goal, with 3 hitting the target.
| Team | Possession | Shots (on target) | xG | Dangerous Attacks |
|---|---|---|---|---|
 Atletico Madrid | 61% | 6 (3) | 1.16 | 55 |
 Villarreal | 39% | 5 (1) | 0.96 | 46 |
Liverpool vs Atletico Madrid Stats
Key Stats
| Liverpool | Atletico Madrid | |
|---|---|---|
| 1 | Attacking Strength | 1.53 |
| 0.66 | Defence Strength | 0.95 |
| 2.5 | Points Per Game | 1.7 |
| 8/10 | WIN | 5/10 |
| 1/10 | DRAW | 2/10 |
| 2/10 | Clean Sheets | 4/10 |
| 8/10 | BTTS | 4/10 |
| 8/10 | Over 2.5 Goals | 4/10 |
| 2.6 | Average Scored | 1.5 |
Goals Scored vs Goals Conceded
Liverpool are averaging 2.6 goals scored and 1.5 conceded per match, while Atletico Madrid average 1.5 scored and 1.0 conceded per game.
Liverpool 26-15
Atletico Madrid 15-10
What are the odds for this match?
Liverpool to win: @1.571
Draw: @4.2
Atletico Madrid to win: @5.5
Lineups
Liverpool (4-3-3) : Alisson, Jeremie Frimpong, Ibrahima Konate, Virgil Van Dijk, Andy Robertson, Ryan Gravenberch, Florian Wirtz, Dominik Szoboszlai, Mohamed Salah, Alexander Isak, Cody Gakpo
Atletico Madrid (4-4-2) : Jan Oblak, Marcos Llorente, Robin Le Normand, Clement Lenglet, Javi Galan, Giuliano Simeone, Pablo Barrios, Conor Gallagher, Nico Gonzalez, Giacomo Raspadori, Antoine Griezmann