Our Santos Laguna vs Cruz Azul Prediction: 1-2
Santos Laguna vs Cruz Azul in the Mexico Liga MX is scheduled for an 01:00 GMT kick-off on Wednesday March 4, 2026. We predict a 1-2 away victory, but with both teams finding the net regularly, BTTS is also a strong betting option.
This Santos Laguna vs Cruz Azul prediction is backed by a deep dive into both teams' recent performances, key stats and head-to-head history — all of which you'll find detailed below to help you make an informed betting decision.
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Recent Form Insights
Santos Laguna's Last Match – Queretaro vs Santos Laguna
Santos Laguna will be determined to find a winning touch after a 2-2 Mexico Liga MX draw against Queretaro on February 28. In that match, Santos Laguna controlled 61% of possession and managed 14 shots on goal, with 4 hitting the target.
| Team | Possession | Shots (on target) | xG | Dangerous Attacks |
|---|---|---|---|---|
 Queretaro | 39% | 17 (7) | 4.13 | 35 |
 Santos Laguna | 61% | 14 (4) | 2.25 | 29 |
Cruz Azul's Last Match – Monterrey vs Cruz Azul
Cruz Azul will hope to extend their good run following a 2-0 Mexico Liga MX win against Monterrey on March 1. In that match, Cruz Azul recorded 44% possession, firing 7 shots at goal, with 7 on target.
| Team | Possession | Shots (on target) | xG | Dangerous Attacks |
|---|---|---|---|---|
 Monterrey | 56% | 12 (3) | 1.06 | 58 |
 Cruz Azul | 44% | 7 (7) | 1.55 | 34 |
Santos Laguna vs Cruz Azul Stats
Key Stats
| Santos Laguna | Cruz Azul | |
|---|---|---|
| 0.8 | Attacking Strength | 1.15 |
| 1.07 | Defence Strength | 0.68 |
| 0.5 | Points Per Game | 2.5 |
| 1/10 | WIN | 8/10 |
| 2/10 | DRAW | 1/10 |
| 1/10 | Clean Sheets | 5/10 |
| 8/10 | BTTS | 5/10 |
| 9/10 | Over 2.5 Goals | 6/10 |
| 1.1 | Average Scored | 2.3 |
Goals Scored vs Goals Conceded
Santos Laguna are averaging 1.1 goals scored and 2.7 conceded per match, while Cruz Azul average 2.3 scored and 0.8 conceded per game.
Santos Laguna 11-27
Cruz Azul 23-8
What are the odds for this match?
Santos Laguna to win: @5.75
Draw: @4.1
Cruz Azul to win: @1.55
Lineups
Santos Laguna (4-2-3-1) : Carlos Acevedo, Emanuel Echeverria, Bruno Amione, Haret Ortega, Kevin Picon, Javier Guemez, Aldo Lopez, Cristian Dajome, Ezequiel Bullaude, Fran Villalba, Luis Gomez
Cruz Azul (3-4-3) : Andres Gudino, Willer Ditta, Erik Lira, Gonzalo Piovi, Amaury Morales Rosas, Carlos Rodriguez, Jeremy Marquez, Carlos Rodolfo Rotondi, Jose Paradela, Nicolas Ibanez, Agustin Palavecino
Cruz Azul 
Toluca 
Chivas Guadalajara 
Pachuca 
Unam Pumas 
Tigres UANL 
Atlas 
Club America 
Monterrey 
Puebla 
Atletico San Luis 
Juarez FC 
Leon 
Mazatlan FC 
Tijuana 
Necaxa 
Queretaro 
Santos Laguna