Our Monterrey vs Santos Laguna Prediction: 3-1
Monterrey vs Santos Laguna in the Mexico Liga MX is scheduled for an 01:00 GMT kick-off on Sunday September 28, 2025. A 3-1 win for the home side is our main prediction, though over 2.5 goals looks like a valuable bet given both teams’ attacking tendencies.
This Monterrey vs Santos Laguna prediction is backed by a deep dive into both teams' recent performances, key stats and head-to-head history — all of which you'll find detailed below to help you make an informed betting decision.
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Recent Form Insights
Monterrey's Last Match – Toluca vs Monterrey
Monterrey must win to recover from their recent 2-6 Mexico Liga MX defeat against Toluca on September 25 and regain momentum. In that match, Monterrey saw 53% of the ball and created 8 goal attempts, with 7 on target.
| Team | Possession | Shots (on target) | xG | Dangerous Attacks |
|---|---|---|---|---|
 Toluca | 47% | 11 (13) | 3.38 | 0 |
 Monterrey | 53% | 8 (7) | 2.55 | 0 |
Santos Laguna's Last Match – Santos Laguna vs Tijuana
Santos Laguna must win to build on their momentum after securing a hard-fought 1-0 Mexico Liga MX victory over Tijuana in their last outing. In that match, Santos Laguna recorded 47% possession, firing 11 shots at goal, with 6 on target.
| Team | Possession | Shots (on target) | xG | Dangerous Attacks |
|---|---|---|---|---|
 Santos Laguna | 47% | 11 (6) | 1.46 | 28 |
 Tijuana | 53% | 9 (1) | 2.02 | 48 |
Monterrey vs Santos Laguna Stats
Key Stats
| Monterrey | Santos Laguna | |
|---|---|---|
| 1.36 | Attacking Strength | 0.87 |
| 0.95 | Defence Strength | 1.42 |
| 1.7 | Points Per Game | 0.7 |
| 5/10 | WIN | 2/10 |
| 2/10 | DRAW | 1/10 |
| 2/10 | Clean Sheets | 2/10 |
| 7/10 | BTTS | 6/10 |
| 7/10 | Over 2.5 Goals | 7/10 |
| 2.1 | Average Scored | 1 |
Goals Scored vs Goals Conceded
Monterrey are averaging 2.1 goals scored and 1.9 conceded per match, while Santos Laguna average 1.0 scored and 2.0 conceded per game.
Monterrey 21-19
Santos Laguna 10-20
What are the odds for this match?
Monterrey to win: @1.333
Draw: @5.75
Santos Laguna to win: @7
Lineups
Monterrey (4-4-2) : Santiago Mele, Ricardo Chavez, Sergio Ramos, Fidel Ambriz, Gerardo Arteaga, Oliver Torres, Stefan Medina, Jesus Corona, Anthony Martial, German Berterame, Lucas Ocampos
Santos Laguna (4-4-2) : Carlos Acevedo, Bruno Amione, Jonathan Perez, Aldo Lopez, Jose Abella, Javier Guemez, Kevin Balanta, Cristian Dajome, Jesus Ocejo, Ramiro Sordo, Salvador Mariscal